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Challenges and Opportunities for Small Molecule Aptamer Development

Aptamers are single-stranded oligonucleotides that bind to targets with high affinity and selectivity. Their use as molecular recognition elements has emerged as a viable approach for biosensing, diagnostics, and therapeutics. Despite this potential, relatively few aptamers exist that bind to small...

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Detalhes bibliográficos
Main Authors: McKeague, Maureen, DeRosa, Maria C.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488411/
https://ncbi.nlm.nih.gov/pubmed/23150810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/748913
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