Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization

The vaccine-mediated elicitation of antibodies (Abs) capable of neutralizing diverse HIV-1 strains has been a long-standing goal. To understand how broadly neutralizing antibodies (bNAbs) can be elicited, we identified, characterized, and tracked five neutralizing Ab lineages targeting the HIV-1-fus...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cell
Asıl Yazarlar: Kong, Rui, Duan, Hongying, Sheng, Zizhang, Xu, Kai, Acharya, Priyamvada, Chen, Xuejun, Cheng, Cheng, Dingens, Adam S., Gorman, Jason, Sastry, Mallika, Shen, Chen-Hsiang, Zhang, Baoshan, Zhou, Tongqing, Chuang, Gwo-Yu, Chao, Cara W., Gu, Ying, Jafari, Alexander J., Louder, Mark K., O’Dell, Sijy, Rowshan, Ariana P., Viox, Elise G., Wang, Yiran, Choi, Chang W., Corcoran, Martin M., Corrigan, Angela R., Dandey, Venkata P., Eng, Edward T., Geng, Hui, Foulds, Kathryn E., Guo, Yicheng, Kwon, Young D., Lin, Bob, Liu, Kevin, Mason, Rosemarie D., Nason, Martha C., Ohr, Tiffany Y., Ou, Li, Rawi, Reda, Sarfo, Edward K., Schön, Arne, Todd, John P., Wang, Shuishu, Wei, Hui, Wu, Winston, Mullikin, James C., Bailer, Robert T., Doria-Rose, Nicole A., Hedestam, Gunilla B. Karlsson, Scorpio, Diana G., Overbaugh, Julie, Bloom, Jesse D., Carragher, Bridget, Potter, Clinton S., Shapiro, Lawrence, Kwong, Peter D., Mascola, John R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755680/
https://ncbi.nlm.nih.gov/pubmed/31348886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.06.030
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