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Systematic minimization of RNA ligase ribozyme through large-scale design-synthesis-sequence cycles
Template-directed RNA ligation catalyzed by an RNA enzyme (ribozyme) is a plausible and important reaction that could have been involved in transferring genetic information during prebiotic evolution. Laboratory evolution experiments have yielded several classes of ligase ribozymes, but their minima...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6755084/ https://ncbi.nlm.nih.gov/pubmed/31504757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz729 |
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