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Controlling Mammalian Gene Expression by Allosteric Hepatitis Delta Virus Ribozymes
[Image: see text] We engineered small molecule responsive allosteric ribozymes based on the genomic hepatitis delta virus (HDV) ribozyme by replacing the P4-L4 stem-loop with an RNA aptamer through a connector stem. When embedded in the 3′ untranslated region of a reporter gene mRNA, these RNA devic...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical Society
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3874218/ https://ncbi.nlm.nih.gov/pubmed/23697539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/sb400037a |
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