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Solution structure and biochemical characterization of a spare part protein that restores activity to an oxygen-damaged glycyl radical enzyme

Glycyl radical enzymes (GREs) utilize a glycyl radical cofactor to carry out a diverse array of chemically challenging enzymatic reactions in anaerobic bacteria. Although the glycyl radical is a powerful catalyst, it is also oxygen sensitive such that oxygen exposure causes cleavage of the GRE at th...

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Detalhes bibliográficos
Publicado no:J Biol Inorg Chem
Main Authors: Bowman, Sarah E.J., Backman, Lindsey R.F., Bjork, Rebekah E., Andorfer, Mary C., Yori, Santiago, Caruso, Alessio, Stultz, Collin M., Drennan, Catherine L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754787/
https://ncbi.nlm.nih.gov/pubmed/31250200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-019-01681-2
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