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Exploring a Ring-Closing Metathesis Approach to the Archazolid Macrocycle
The synthesis of a new “eastern domain” of a proposed dihydroarchazolid analogue is described along with initial results from attempted macrocyclization by RCM. This work has revealed a competing backbiting process that may be preventable by alcohol functionalization and installation of a metathesis...
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| Udgivet i: | Synthesis (Stuttg) |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6754729/ https://ncbi.nlm.nih.gov/pubmed/31543555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0034-1379003 |
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