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Kinetically E-Selective Macrocyclic Ring-Closing Metathesis
Macrocyclic compounds are central to discovery of new drugs but their preparation is often challenging because of the energy barrier required for bringing together and fusing the two ends of an acyclic precursor(1). Ring-closing metathesis (RCM) (2,3,4) is a catalytic process that has allowed access...
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| Publié dans: | Nature |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5247355/ https://ncbi.nlm.nih.gov/pubmed/28068669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature20800 |
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