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Kinetically E-Selective Macrocyclic Ring-Closing Metathesis

Macrocyclic compounds are central to discovery of new drugs but their preparation is often challenging because of the energy barrier required for bringing together and fusing the two ends of an acyclic precursor(1). Ring-closing metathesis (RCM) (2,3,4) is a catalytic process that has allowed access...

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Dades bibliogràfiques
Publicat a:Nature
Autors principals: Shen, Xiao, Nguyen, Thach T., Koh, Ming Joo, Xu, Dongmin, Speed, Alexander W. H., Schrock, Richard R., Hoveyda, Amir H.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247355/
https://ncbi.nlm.nih.gov/pubmed/28068669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature20800
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