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Poly(ADP-ribose) Polymerase 2 Recruits Replication Protein A to Sites of LINE-1 Integration to Facilitate Retrotransposition
Long INterspersed Element-1 (L1) retrotransposition poses a threat to genome integrity and cells have evolved mechanisms to restrict retrotransposition. However, how cellular proteins facilitate L1 retrotransposition requires elucidation. Here, we demonstrate that single strand DNA breaks induced by...
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| 出版年: | Mol Cell |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6754305/ https://ncbi.nlm.nih.gov/pubmed/31473101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.07.018 |
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