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Poly(ADP-ribose) Polymerase 2 Recruits Replication Protein A to Sites of LINE-1 Integration to Facilitate Retrotransposition
Long INterspersed Element-1 (L1) retrotransposition poses a threat to genome integrity and cells have evolved mechanisms to restrict retrotransposition. However, how cellular proteins facilitate L1 retrotransposition requires elucidation. Here, we demonstrate that single strand DNA breaks induced by...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6754305/ https://ncbi.nlm.nih.gov/pubmed/31473101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.07.018 |
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