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A 3′ poly(A) tract is required for LINE-1 retrotransposition
L1 retrotransposons express proteins (ORF1p and ORF2p) that preferentially mobilize their encoding RNA in cis, but they also can mobilize Alu RNA and, more rarely, cellular mRNAs in trans. Although these RNAs differ in sequence, each ends in a 3′ polyadenosine (poly(A)) tract. Here, we replace the L...
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| Publicat a: | Mol Cell |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4671821/ https://ncbi.nlm.nih.gov/pubmed/26585388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.10.012 |
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