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Influence of the Novel Histamine H3 Receptor Antagonist/Inverse Agonist M39 on Gastroprotection and PGE2 Production Induced by (R)-Alpha-Methylhistamine in C57BL/6 Mice

The role of histamine H3 receptors (H3Rs) in the regulation of gastroprotection and production of prostaglandin E2 (PGE2) as well as somatostatin remains contradictory. Therefore, the effects of the H3R antagonist/inverse agonist M39 on in vivo acidified ethanol-induced gastric ulcers and gastric ac...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Bastaki, Salim M. A., Amir, Naheed, Więcek, Małgorzata, Kieć-Kononowicz, Katarzyna, Sadek, Bassem
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6751319/
https://ncbi.nlm.nih.gov/pubmed/31572174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00966
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