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MLL1 is required for PAX7 expression and satellite cell self-renewal in mice
PAX7 is a paired-homeobox transcription factor that specifies the myogenic identity of muscle stem cells and acts as a nodal factor by stimulating proliferation while inhibiting differentiation. We previously found that PAX7 recruits the H3K4 methyltransferases MLL1/2 to epigenetically activate targ...
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| 發表在: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6751293/ https://ncbi.nlm.nih.gov/pubmed/31534153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12086-9 |
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