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Pax7 directs postnatal renewal and propagation of myogenic satellite cells but not their specification

The paired-box transcription factor Pax7 has been claimed to specify the muscle stem cell lineage since inactivation of Pax7 led to a failure to detect muscle satellite cells. Here we show that muscles of juvenile Pax7(−/−) mice at P11 contain a reduced but substantial number of satellite cells. Nei...

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Detalhes bibliográficos
Main Authors: Oustanina, Svetlana, Hause, Gerd, Braun, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC514519/
https://ncbi.nlm.nih.gov/pubmed/15282552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600346
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