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Synthesis of Indolines and Derivatives via Aza-Heck Cyclization

For the first time, an aza-Heck cyclization that allows the preparation of indoline scaffolds is described. Using N-hydroxy anilines as electrophiles, which can be easily accessed from the corresponding nitroarenes, this method provides indolines bearing pendant functionality and complex ring topolo...

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Bibliografische gegevens
Gepubliceerd in:Angew Chem Int Ed Engl
Hoofdauteurs: Xu, Feiyang, Korch, Katerina M., Watson, Donald A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6750995/
https://ncbi.nlm.nih.gov/pubmed/31310448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201907758
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