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Female Sex and Brain-Selective Estrogen Benefit α-Synuclein Tetramerization and the PD-like Motor Syndrome in 3K Transgenic Mice

Many studies report a higher risk for Parkinson's disease (PD) and younger age of onset in men. This, and the fact that the neuropathological process underlying PD symptoms may begin before menopause, suggests that estrogen-based hormone therapy could modify this higher risk in males. However,...

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Опубликовано в: :J Neurosci
Главные авторы: Rajsombath, Molly M., Nam, Alice Y., Ericsson, Maria, Nuber, Silke
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6750939/
https://ncbi.nlm.nih.gov/pubmed/31405930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0313-19.2019
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