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Insights into the pathogenesis of catecholaminergic polymorphic ventricular tachycardia from engineered human heart tissue
BACKGROUND: Modeling of human arrhythmias using induced pluripotent stem cell-derived cardiomyocytes has focused on single cell phenotypes. However, arrhythmias are the emergent properties of cells assembled into tissues, and the impact of inherited arrhythmia mutations on tissue-level properties of...
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| Publié dans: | Circulation |
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| Auteurs principaux: | , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6750809/ https://ncbi.nlm.nih.gov/pubmed/31311300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.119.039711 |
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