Preclinical and translational pharmacokinetics of a novel THIOMAB™ antibody-antibiotic conjugate against Staphylococcus aureus

DSTA4637S, a novel THIOMAB™ antibody-antibiotic conjugate (TAC) against Staphylococcus aureus (S. aureus), is currently being investigated as a potential therapy for complicated S. aureus bloodstream infections. DSTA4637S is composed of a monoclonal THIOMAB(TM) IgG1 recognizing S. aureus linked to a...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Deng, Rong, Zhou, Chenguang, Li, Dongwei, Cai, Hao, Sukumaran, Siddharth, Carrasco-Triguero, Montserrat, Saad, Ola, Nazzal, Denise, Lowe, Christopher, Ramanujan, Saroja, Kamath, Amrita V.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
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Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748576/
https://ncbi.nlm.nih.gov/pubmed/31219754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1627152
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