GSE4 peptide suppresses oxidative and telomere deficiencies in ataxia telangiectasia patient cells

Ataxia telangiectasia (AT) is a genetic disease caused by mutations in the ATM gene but the mechanisms underlying AT are not completely understood. Key functions of the ATM protein are to sense and regulate cellular redox status and to transduce DNA double-strand break signals to downstream effector...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Cell Death Differ
Hlavní autoři: Pintado-Berninches, Laura, Fernandez-Varas, Beatriz, Benitez-Buelga, Carlos, Manguan-Garcia, Cristina, Serrano-Benitez, Almudena, Iarriccio, Laura, Carrillo, Jaime, Guenechea, Guillermo, Egusquiaguirre, Susana P., Pedraz, Jose-Luis, Hernández, Rosa M., Igartua, Manoli, Arias-Salgado, Elena G., Cortés-Ledesma, Felipe, Sastre, Leandro, Perona, Rosario
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748109/
https://ncbi.nlm.nih.gov/pubmed/30670828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0272-7
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky