GSE4, a Small Dyskerin- and GSE24.2-Related Peptide, Induces Telomerase Activity, Cell Proliferation and Reduces DNA Damage, Oxidative Stress and Cell Senescence in Dyskerin Mutant Cells

Dyskeratosis congenita is an inherited disease caused by mutations in genes coding for telomeric components. It was previously reported that expression of a dyskerin-derived peptide, GSE24.2, increases telomerase activity, regulates gene expression and decreases DNA damage and oxidative stress in dy...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Iarriccio, Laura, Manguán-García, Cristina, Pintado-Berninches, Laura, Mancheño, José Miguel, Molina, Antonio, Perona, Rosario, Sastre, Leandro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646510/
https://ncbi.nlm.nih.gov/pubmed/26571381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142980
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