Reprogramming miRNAs global expression orchestrates development of drug resistance in BRAF mutated melanoma

Drug resistance imposes severe limitations to the efficacy of targeted therapy in BRAF-mutated metastatic melanoma. Although this issue has been mitigated by the development of combination therapies with BRAF plus MEK inhibitors, drug resistance inevitably occurs with time and results in clinical re...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Fattore, Luigi, Ruggiero, Ciro Francesco, Pisanu, Maria Elena, Liguoro, Domenico, Cerri, Andrea, Costantini, Susan, Capone, Francesca, Acunzo, Mario, Romano, Giulia, Nigita, Giovanni, Mallardo, Domenico, Ragone, Concetta, Carriero, Maria Vincenza, Budillon, Alfredo, Botti, Gerardo, Ascierto, Paolo Antonio, Mancini, Rita, Ciliberto, Gennaro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748102/
https://ncbi.nlm.nih.gov/pubmed/30254376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0205-5
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