MORC2 regulates C/EBPα-mediated cell differentiation via sumoylation

The expression and activity of CCAAT/enhancer-binding protein α (C/EBPα) are involved in sumoylation modification, which is critical to divert normal cells from differentiation to proliferation. However, the role and underlying mechanism of C/EBPα in cancer is poorly understood. Human MORC2 (microrc...

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Veröffentlicht in:Cell Death Differ
Hauptverfasser: Liu, Jia, Zhang, Qing, Ruan, Banlai, Chen, Wei, Zheng, Jianyu, Xu, Buxuan, Jiang, Peijia, Miao, Zhifeng, Li, Feng, Guo, Jessie Yanxiang, Cao, Liu, Wang, Guiling
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748086/
https://ncbi.nlm.nih.gov/pubmed/30644437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0259-4
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