Differential effects of sumoylation on the activities of CCAAT enhancer binding protein alpha (C/EBPα) p42 versus p30 may contribute in part, to aberrant C/EBPα activity in acute leukemias

In this study, we have examined the role of post-translational modification of the myeloid master regulator C/EBPα by small ubiquitin-related modifier (SUMO). We have used transient transfection analysis, oligonucleotide pulldown assays and chromatin immuno-precititation in all-trans retinoic acid (...

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Detalhes bibliográficos
Main Authors: Hankey, William, Silver, Matthew, Sun, B.S.Hong, Zibello, Terry, Berliner, Nancy, Khanna-Gupta, Arati
Formato: Artigo
Idioma:Inglês
Publicado em: PAGEPress Publications 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3238474/
https://ncbi.nlm.nih.gov/pubmed/22184527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4081/hr.2011.e5
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