PAK1-mediated MORC2 phosphorylation promotes gastric tumorigenesis

To date, microrchidia (MORC) family CW-type zinc-finger 2 (MORC2), has been found to be involved in p21-activated kinase1 (PAK1) pathway to maintain genomic integrity. Here, we explore its novel role in cancer. We demonstrate that PAK1-mediated MORC2 phosphorylation promotes cell cycle progression,...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wang, Guiling, Song, Yanyan, Liu, Tong, Wang, Chunyu, Zhang, Qing, Liu, Furong, Cai, Xinze, Miao, Zhifeng, Xu, Hongde, Xu, Huimian, Cao, Liu, Li, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496403/
https://ncbi.nlm.nih.gov/pubmed/25888627
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