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PAK1-mediated MORC2 phosphorylation promotes gastric tumorigenesis
To date, microrchidia (MORC) family CW-type zinc-finger 2 (MORC2), has been found to be involved in p21-activated kinase1 (PAK1) pathway to maintain genomic integrity. Here, we explore its novel role in cancer. We demonstrate that PAK1-mediated MORC2 phosphorylation promotes cell cycle progression,...
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Udgivet i: | Oncotarget |
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Main Authors: | , , , , , , , , , , , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Impact Journals LLC
2015
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4496403/ https://ncbi.nlm.nih.gov/pubmed/25888627 |
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