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Radical Stress Is More Cytotoxic in the Nucleus than in Other Organelles
Cells are exposed to reactive oxygen species (ROS) as a by-product of mitochondrial metabolism, especially under hypoxia. ROS are also enzymatically generated at the plasma membrane during inflammation. Radicals cause cellular damage leading to cell death, as they react indiscriminately with surroun...
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| Udgivet i: | Int J Mol Sci |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6747261/ https://ncbi.nlm.nih.gov/pubmed/31450682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20174147 |
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