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Radical Stress Is More Cytotoxic in the Nucleus than in Other Organelles

Cells are exposed to reactive oxygen species (ROS) as a by-product of mitochondrial metabolism, especially under hypoxia. ROS are also enzymatically generated at the plasma membrane during inflammation. Radicals cause cellular damage leading to cell death, as they react indiscriminately with surroun...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Paardekooper, Laurent M., van Vroonhoven, Ellen, ter Beest, Martin, van den Bogaart, Geert
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6747261/
https://ncbi.nlm.nih.gov/pubmed/31450682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20174147
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