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Radical Stress Is More Cytotoxic in the Nucleus than in Other Organelles

Cells are exposed to reactive oxygen species (ROS) as a by-product of mitochondrial metabolism, especially under hypoxia. ROS are also enzymatically generated at the plasma membrane during inflammation. Radicals cause cellular damage leading to cell death, as they react indiscriminately with surroun...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Paardekooper, Laurent M., van Vroonhoven, Ellen, ter Beest, Martin, van den Bogaart, Geert
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6747261/
https://ncbi.nlm.nih.gov/pubmed/31450682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20174147
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