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The Resounding Impact of DNA Repair Deficiency in Prostate Cancer
An estimated one fifth or more of metastatic castration resistant prostate cancer (mCRPC) harbor defects in genes involved in DNA repair pathway (e.g. BRCA2, BRCA1 and others). Early evidence suggests these alterations may be predictive of therapeutic response to PARP inhibitors and platinum chemoth...
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| Publicado no: | Urol Oncol |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6746340/ https://ncbi.nlm.nih.gov/pubmed/29555412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.urolonc.2018.02.014 |
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