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Defective DNA repair mechanisms in prostate cancer: impact of olaparib
The field of prostate oncology has continued to change dramatically. It has truly become a field that is intensely linked to molecular genetic alterations, especially DNA-repair defects. Germline breast cancer 1 gene (BRCA1) and breast cancer 2 gene (BRCA2) mutations are implicated in the highest ri...
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| Publicat a: | Drug Des Devel Ther |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Dove Medical Press
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5338854/ https://ncbi.nlm.nih.gov/pubmed/28280302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S110264 |
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