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Defective DNA repair mechanisms in prostate cancer: impact of olaparib
The field of prostate oncology has continued to change dramatically. It has truly become a field that is intensely linked to molecular genetic alterations, especially DNA-repair defects. Germline breast cancer 1 gene (BRCA1) and breast cancer 2 gene (BRCA2) mutations are implicated in the highest ri...
Enregistré dans:
| Publié dans: | Drug Des Devel Ther |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Dove Medical Press
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5338854/ https://ncbi.nlm.nih.gov/pubmed/28280302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S110264 |
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