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The Resounding Impact of DNA Repair Deficiency in Prostate Cancer
An estimated one fifth or more of metastatic castration resistant prostate cancer (mCRPC) harbor defects in genes involved in DNA repair pathway (e.g. BRCA2, BRCA1 and others). Early evidence suggests these alterations may be predictive of therapeutic response to PARP inhibitors and platinum chemoth...
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| Yayımlandı: | Urol Oncol |
|---|---|
| Yazar: | |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6746340/ https://ncbi.nlm.nih.gov/pubmed/29555412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.urolonc.2018.02.014 |
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