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Hydrogel-coated microneedle arrays for minimally-invasive sampling and sensing of specific circulating nucleic acids from skin interstitial fluid.

Minimally-invasive technologies that can sample and detect cell-free nucleic acid biomarkers from liquid biopsies have recently emerged as clinically useful for early diagnosis of a broad range of pathologies, including cancer. Although blood has been so far the most commonly interrogated body fluid...

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Bibliographic Details
Published in:ACS Nano
Main Authors: Sulaiman, Dana Al, Chang, Jason Y. H., Bennett, Nitasha R., Topouzi, Helena, Higgins, Claire A., Irvine, Darrell J., Ladame, Sylvain
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6746174/
https://ncbi.nlm.nih.gov/pubmed/31411871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.9b04783
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