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Transdermal Influenza Immunization with Vaccine-Coated Microneedle Arrays

BACKGROUND: Influenza is a contagious disease caused by a pathogenic virus, with outbreaks all over the world and thousands of hospitalizations and deaths every year. Due to virus antigenic drift and short-lived immune responses, annual vaccination is required. However, vaccine coverage is incomplet...

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Detalhes bibliográficos
Main Authors: Koutsonanos, Dimitrios G., Martin, Maria del Pilar, Zarnitsyn, Vladimir G., Sullivan, Sean P., Compans, Richard W., Prausnitz, Mark R., Skountzou, Ioanna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651574/
https://ncbi.nlm.nih.gov/pubmed/19274084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004773
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