Microneedle Vaccination with Stabilized Recombinant Influenza Virus Hemagglutinin Induces Improved Protective Immunity

The emergence of the swine-origin 2009 influenza pandemic illustrates the need for improved vaccine production and delivery strategies. Skin-based immunization represents an attractive alternative to traditional hypodermic needle vaccination routes. Microneedles (MNs) can deliver vaccine to the epid...

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Detalhes bibliográficos
Main Authors: Weldon, William C., Martin, Maria P., Zarnitsyn, Vladimir, Wang, Baozhong, Koutsonanos, Dimitrios, Skountzou, Ioanna, Prausnitz, Mark R., Compans, Richard W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Vaccine Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122571/
https://ncbi.nlm.nih.gov/pubmed/21288996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00435-10
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