Effect of Adjuvants on Responses to Skin Immunization by Microneedles Coated with Influenza Subunit Vaccine

Recent studies have demonstrated the effectiveness of vaccine delivery to the skin by vaccine-coated microneedles; however there is little information on the effects of adjuvants using this approach for vaccination. Here we investigate the use of TLR ligands as adjuvants with skin-based delivery of...

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Autores principales: Weldon, William C., Zarnitsyn, Vladimir G., Esser, E. Stein, Taherbhai, Misha T., Koutsonanos, Dimitrios G., Vassilieva, Elena V., Skountzou, Ioanna, Prausnitz, Mark R., Compans, Richard W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405087/
https://ncbi.nlm.nih.gov/pubmed/22848514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041501
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