Delivery of subunit influenza vaccine to skin with microneedles improves immunogenicity and long-lived protection

Influenza infection represents a major socio-economic burden worldwide. Novel delivery methods can render influenza vaccination easier and more acceptable by the public, and importantly confer protection equal or superior to that induced by conventional systemic administration. An attractive target...

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Main Authors: Koutsonanos, Dimitrios G., Vassilieva, Elena V., Stavropoulou, Anastasia, Zarnitsyn, Vladimir G., Esser, E. Stein, Taherbhai, Misha T., Prausnitz, Mark R., Compans, Richard W., Skountzou, Ioanna
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324956/
https://ncbi.nlm.nih.gov/pubmed/22500210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00357
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