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Delivery of subunit influenza vaccine to skin with microneedles improves immunogenicity and long-lived protection

Influenza infection represents a major socio-economic burden worldwide. Novel delivery methods can render influenza vaccination easier and more acceptable by the public, and importantly confer protection equal or superior to that induced by conventional systemic administration. An attractive target...

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Detalhes bibliográficos
Main Authors: Koutsonanos, Dimitrios G., Vassilieva, Elena V., Stavropoulou, Anastasia, Zarnitsyn, Vladimir G., Esser, E. Stein, Taherbhai, Misha T., Prausnitz, Mark R., Compans, Richard W., Skountzou, Ioanna
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324956/
https://ncbi.nlm.nih.gov/pubmed/22500210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00357
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