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Subnanomolar Detection of Oligonucleotides through Templated Fluorogenic Reaction in Hydrogels: Controlling Diffusion to Improve Sensitivity

Oligonucleotide‐templated reactions are valuable tools for nucleic acid sensing both in vitro and in vivo. They are typically carried out under conditions that make any reaction in the absence of template highly unfavorable (most commonly by using a low concentration of reactants), which has a negat...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Al Sulaiman, Dana, Chang, Jason Y. H., Ladame, Sylvain
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502887/
https://ncbi.nlm.nih.gov/pubmed/28382640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201701356
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