Hydrogel-Forming Microneedle Arrays for Enhanced Transdermal Drug Delivery

Unique microneedle arrays prepared from crosslinked polymers, which contain no drug themselves, are described. They rapidly take up skin interstitial fluid upon skin insertion to form continuous, unblockable, hydrogel conduits from attached patch-type drug reservoirs to the dermal microcirculation....

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Main Authors: Donnelly, Ryan F, Singh, Thakur Raghu Raj, Garland, Martin J, Migalska, Katarzyna, Majithiya, Rita, McCrudden, Cian M, Kole, Prashant Laxman, Mahmood, Tuan Mazlelaa Tuan, McCarthy, Helen O, Woolfson, A David
Formato: Artigo
Idioma:Inglês
Publicado: WILEY-VCH Verlag 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627464/
https://ncbi.nlm.nih.gov/pubmed/23606824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adfm.201200864
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