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Hydrogel-forming microneedles enhance transdermal delivery of metformin hydrochloride
We investigated, for the first time, the potential for a hydrogel-forming microneedle (MN) patch to deliver the high-dose drug metformin HCl transdermally in a sustained manner. This may minimize some gastrointestinal side effects and small intestine absorption variations associated with oral delive...
Uloženo v:
| Vydáno v: | J Control Release |
|---|---|
| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Elsevier Science Publishers
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6141810/ https://ncbi.nlm.nih.gov/pubmed/29990526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.07.009 |
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