Chemoptogenetic damage to mitochondria causes rapid telomere dysfunction

Reactive oxygen species (ROS) play important roles in aging, inflammation, and cancer. Mitochondria are an important source of ROS; however, the spatiotemporal ROS events underlying oxidative cellular damage from dysfunctional mitochondria remain unresolved. To this end, we have developed and valida...

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發表在:Proc Natl Acad Sci U S A
Main Authors: Qian, Wei, Kumar, Namrata, Roginskaya, Vera, Fouquerel, Elise, Opresko, Patricia L., Shiva, Sruti, Watkins, Simon C., Kolodieznyi, Dmytro, Bruchez, Marcel P., Van Houten, Bennett
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2019
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PNAS Plus
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744920/
https://ncbi.nlm.nih.gov/pubmed/31451640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1910574116
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