Mechanistic basis of neonatal heart regeneration revealed by transcriptome and histone modification profiling

The adult mammalian heart has limited capacity for regeneration following injury, whereas the neonatal heart can readily regenerate within a short period after birth. To uncover the molecular mechanisms underlying neonatal heart regeneration, we compared the transcriptomes and epigenomes of regenera...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Wang, Zhaoning, Cui, Miao, Shah, Akansha M., Ye, Wenduo, Tan, Wei, Min, Yi-Li, Botten, Giovanni A., Shelton, John M., Liu, Ning, Bassel-Duby, Rhonda, Olson, Eric N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2019
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744882/
https://ncbi.nlm.nih.gov/pubmed/31451669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1905824116
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