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Mechanistic basis of neonatal heart regeneration revealed by transcriptome and histone modification profiling

The adult mammalian heart has limited capacity for regeneration following injury, whereas the neonatal heart can readily regenerate within a short period after birth. To uncover the molecular mechanisms underlying neonatal heart regeneration, we compared the transcriptomes and epigenomes of regenera...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wang, Zhaoning, Cui, Miao, Shah, Akansha M., Ye, Wenduo, Tan, Wei, Min, Yi-Li, Botten, Giovanni A., Shelton, John M., Liu, Ning, Bassel-Duby, Rhonda, Olson, Eric N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744882/
https://ncbi.nlm.nih.gov/pubmed/31451669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1905824116
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