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Macrophages are required for neonatal heart regeneration

Myocardial infarction (MI) leads to cardiomyocyte death, which triggers an immune response that clears debris and restores tissue integrity. In the adult heart, the immune system facilitates scar formation, which repairs the damaged myocardium but compromises cardiac function. In neonatal mice, the...

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Detalhes bibliográficos
Main Authors: Aurora, Arin B., Porrello, Enzo R., Tan, Wei, Mahmoud, Ahmed I., Hill, Joseph A., Bassel-Duby, Rhonda, Sadek, Hesham A., Olson, Eric N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938260/
https://ncbi.nlm.nih.gov/pubmed/24569380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI72181
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