Mechanistic basis of neonatal heart regeneration revealed by transcriptome and histone modification profiling

The adult mammalian heart has limited capacity for regeneration following injury, whereas the neonatal heart can readily regenerate within a short period after birth. To uncover the molecular mechanisms underlying neonatal heart regeneration, we compared the transcriptomes and epigenomes of regenera...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Wang, Zhaoning, Cui, Miao, Shah, Akansha M., Ye, Wenduo, Tan, Wei, Min, Yi-Li, Botten, Giovanni A., Shelton, John M., Liu, Ning, Bassel-Duby, Rhonda, Olson, Eric N.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2019
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744882/
https://ncbi.nlm.nih.gov/pubmed/31451669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1905824116
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