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A cell-free DNA metagenomic sequencing assay that integrates the host injury response to infection

High-throughput metagenomic sequencing offers an unbiased approach to identify pathogens in clinical samples. Conventional metagenomic sequencing, however, does not integrate information about the host, which is often critical to distinguish infection from infectious disease, and to assess the sever...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Cheng, Alexandre Pellan, Burnham, Philip, Lee, John Richard, Cheng, Matthew Pellan, Suthanthiran, Manikkam, Dadhania, Darshana, De Vlaminck, Iwijn
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744880/
https://ncbi.nlm.nih.gov/pubmed/31451660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906320116
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