A cell-free DNA metagenomic sequencing assay that integrates the host injury response to infection

High-throughput metagenomic sequencing offers an unbiased approach to identify pathogens in clinical samples. Conventional metagenomic sequencing, however, does not integrate information about the host, which is often critical to distinguish infection from infectious disease, and to assess the sever...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Cheng, Alexandre Pellan, Burnham, Philip, Lee, John Richard, Cheng, Matthew Pellan, Suthanthiran, Manikkam, Dadhania, Darshana, De Vlaminck, Iwijn
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2019
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744880/
https://ncbi.nlm.nih.gov/pubmed/31451660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906320116
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