Cell-Free DNA in Blood Reveals Significant Cell, Tissue and Organ Specific injury and Predicts COVID-19 Severity

COVID-19 primarily affects the lungs, but evidence of systemic disease with multi-organ involvement is emerging. Here, we developed a blood test to broadly quantify cell, tissue, and organ specific injury due to COVID-19, using genome-wide methylation profiling of circulating cell-free DNA in plasma...

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Bibliografiske detaljer
Udgivet i:medRxiv
Main Authors: Cheng, Alexandre Pellan, Cheng, Matthew Pellan, Gu, Wei, Lenz, Joan Sesing, Hsu, Elaine, Schurr, Erwin, Bourque, Guillaume, Bourgey, Mathieu, Ritz, Jerome, Marty, Francisco, Chiu, Charles Y., Vinh, Donald Cuong, Vlaminck, Iwijn De
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7402071/
https://ncbi.nlm.nih.gov/pubmed/32766608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.07.27.20163188
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