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A cell-free DNA metagenomic sequencing assay that integrates the host injury response to infection

High-throughput metagenomic sequencing offers an unbiased approach to identify pathogens in clinical samples. Conventional metagenomic sequencing, however, does not integrate information about the host, which is often critical to distinguish infection from infectious disease, and to assess the sever...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Cheng, Alexandre Pellan, Burnham, Philip, Lee, John Richard, Cheng, Matthew Pellan, Suthanthiran, Manikkam, Dadhania, Darshana, De Vlaminck, Iwijn
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2019
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744880/
https://ncbi.nlm.nih.gov/pubmed/31451660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906320116
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