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A cell-free DNA metagenomic sequencing assay that integrates the host injury response to infection

High-throughput metagenomic sequencing offers an unbiased approach to identify pathogens in clinical samples. Conventional metagenomic sequencing, however, does not integrate information about the host, which is often critical to distinguish infection from infectious disease, and to assess the sever...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Cheng, Alexandre Pellan, Burnham, Philip, Lee, John Richard, Cheng, Matthew Pellan, Suthanthiran, Manikkam, Dadhania, Darshana, De Vlaminck, Iwijn
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744880/
https://ncbi.nlm.nih.gov/pubmed/31451660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906320116
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