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Efficient genome-wide first-generation phenotypic screening system in mice using the piggyBac transposon

Genome-wide phenotypic screens provide an unbiased way to identify genes involved in particular biological traits, and have been widely used in lower model organisms. However, cost and time have limited the utility of such screens to address biological and disease questions in mammals. Here we repor...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Chang, Hao, Pan, Yukun, Landrette, Sean, Ding, Sheng, Yang, Dong, Liu, Lufang, Tian, Lei, Chai, Hongyan, Li, Peining, Li, Da-Ming, Xu, Tian
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744845/
https://ncbi.nlm.nih.gov/pubmed/31451639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906354116
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