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Efficient genome-wide first-generation phenotypic screening system in mice using the piggyBac transposon
Genome-wide phenotypic screens provide an unbiased way to identify genes involved in particular biological traits, and have been widely used in lower model organisms. However, cost and time have limited the utility of such screens to address biological and disease questions in mammals. Here we repor...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6744845/ https://ncbi.nlm.nih.gov/pubmed/31451639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906354116 |
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