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Mechanisms of rDNA copy number maintenance

Ribosomal DNA (rDNA), the genes encoding the RNA components of ribosomes (rRNA), are highly repetitive in all eukaryotic genomes, containing 100s to 1000s of copies, to meet the demand for ribosome biogenesis. rDNA genes are arranged in large stretches of tandem repeats, forming loci that are highly...

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Detalles Bibliográficos
Publicado en:Trends Genet
Main Authors: Nelson, Jonathan O., Watase, George J., Warsinger-Pepe, Natalie, Yamashita, Yukiko M.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744303/
https://ncbi.nlm.nih.gov/pubmed/31395390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2019.07.006
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